Hotels in Tuscumbia, Missouri

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Facts about staying in Tuscumbia, MO

Find useful tips and insights about staying in Tuscumbia to help you make the most of your experience. FAQs were last updated on 10 December 2025.

  • What are the best hotels in Tuscumbia?

    Great Cabin on Osage River in Tuscumbia, MO is a very popular hotel in Tuscumbia, with a score of 10.0 from 21 reviews.

  • How many hotels are there in Tuscumbia?

    In total, there are 7 hotels to choose from in Tuscumbia, compared to 13,025 properties in Missouri.

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