Hotels in Sikeston
Search and compare Sikeston hotels from hundreds of travel sites on HotelsCombined and save.
Sikeston, United States
2 May — 3 May2
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Travel insights for hotels in Sikeston
Use these up-to-date, data-driven insights about booking a hotel in Sikeston including ideal times to book, pricing trends, and more.
What is the cheapest month to book a hotel in Sikeston?
The cheapest month to book a hotel in Sikeston is September ($232). Conversely, the most expensive month to stay in Sikeston is June ($319).
What is the cheapest day to stay in a hotel in Sikeston?
The cheapest day to stay in Sikeston is Monday ($247). On the other hand, travelers can expect to pay the most on Thursday, when the average nightly price is $309.
Cheapest hotels in Sikeston, Missouri
Discover affordable stays in Sikeston that provide a quality experience without breaking the bank. Hotels in Sikeston can be found for as low as $124 per night. There is currently one property in Sikeston that can be booked for this price. Travel Inn and Suites is one of the hotels that can be booked for the lowest price in Sikeston. Price data was last updated on 25 April 2025
Currently, these are the lowest-priced hotels in Sikeston we've come across for the dates selected. Prices can differ depending on the dates selected, so use the search form to browse more options if you have flexibility.
Show all 15 hotels
100 Matthews Lane, Sikeston, MO, United States
4.8 km from city centre
Free Wi-Fi
Parking
$124
Avg. per night
2609 East Malone Avenue, Sikeston, MO, United States
4.5 km from city centre
Free Wi-Fi
Parking
$126
Avg. per night
110 South Interstate Drive, Sikeston, MO, United States
5.4 km from city centre
Free Wi-Fi
Parking
$136
Avg. per night
220 South Interstate Drive, Sikeston, MO, United States
5.3 km from city centre
Free Wi-Fi
$146
Avg. per night
2602 East Malone Avenue, Sikeston, MO, United States
4.8 km from city centre
Pool
Free Wi-Fi
Parking
$164
Avg. per night
120 South Interstate Drive, Sikeston, MO, United States
5.3 km from city centre
Pool
Free Wi-Fi
Parking
$167
Avg. per night
109 Matthews Lane, Sikeston, MO, United States
4.8 km from city centre
Pool
Free Wi-Fi
Parking
$172
Avg. per night
2608 East Malone Avenue, Sikeston, MO, United States
4.5 km from city centre
Pool
Free Wi-Fi
Parking
$216
Avg. per night
1240 Commerce Drive, Sikeston, MO, United States
2.2 km from city centre
Pool
Free Wi-Fi
Parking
$216
Avg. per night
115 Hospitality Drive, Sikeston, MO, United States
2.1 km from city centre
Pool
Free Wi-Fi
Parking
$257
Avg. per night