What are the best hotels in Sikeston?

Drury Inn & Suites Sikeston is a very popular hotel in Sikeston, with a score of 9.3 from 1,244 reviews. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) (7.2 from 611 reviews) and Best Western Plus Sikeston (7.5 from 618 reviews) are also highly rated Sikeston hotels based on recent feedback from HotelsCombined users.

What are some other cities to stay in when visiting Missouri?

In addition to Sikeston, travellers opt to visit Kansas City when visiting Missouri.

How many hotels are there in Sikeston?

In total, there are 16 hotels to choose from in Sikeston, compared to 15,264 properties in Missouri.

Sikeston Hotels: 16 Cheap Sikeston Hotel Deals

Travel insights for hotels in Sikeston

Use these up-to-date, data-driven insights about booking a hotel in Sikeston including ideal times to book, pricing trends, and more.

What is the cheapest month to book a hotel in Sikeston?

The cheapest month to book a hotel in Sikeston is January ($145). Conversely, the most expensive month to stay in Sikeston is September ($233).

What is the cheapest day to stay in a hotel in Sikeston?

The cheapest day to stay in Sikeston is Wednesday ($161). On the other hand, travellers can expect to pay the most on Friday, when the average nightly price is $234.

How far ahead should you book a hotel in Sikeston?

Save money by booking a hotel at least 46 days before your trip to Sikeston. The lowest price found when booking 46 days ahead was $105 per night.

Find deals

Cheapest hotels in Sikeston, Missouri

Currently, these are the lowest-priced hotels in Sikeston we've come across for the dates selected. Prices can differ depending on the dates selected, so use the search form to browse more options if you have flexibility.

Show all 16 hotels

Super 8 by Wyndham Sikeston/Miner Area

2609 East Malone Avenue, Sikeston, MO, United States

4.5 km from city centre

Free Wi-Fi

Parking

$100

Avg. per night

View Deal

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane, Sikeston, MO, United States

4.8 km from city centre

Free Wi-Fi

Air conditioning

$102

Avg. per night

View Deal

Days Inn and Suites by Wyndham Sikeston

220 South Interstate Drive, Sikeston, MO, United States

5.3 km from city centre

Free Wi-Fi

Parking

$102

Avg. per night

View Deal

Drury Inn & Suites Sikeston

2608 East Malone Avenue, Sikeston, MO, United States

4.5 km from city centre

Pool

Free Wi-Fi

Parking

$146

Avg. per night

View Deal

Best Western Plus Sikeston

120 South Interstate Drive, Sikeston, MO, United States

5.3 km from city centre

Pool

Free Wi-Fi

Parking

$153

Avg. per night

View Deal

Comfort Inn & Suites Sikeston I-55

109 Matthews Lane, Sikeston, MO, United States

4.8 km from city centre

Pool

Free Wi-Fi

Parking

$160

Avg. per night

View Deal

Hampton Inn by Hilton Sikeston

1240 Commerce Drive, Sikeston, MO, United States

2.3 km from city centre

Pool

Free Wi-Fi

Parking

$178

Avg. per night

View Deal

Holiday Inn Express & Suites Sikeston By IHG

115 Hospitality Drive, Sikeston, MO, United States

2.1 km from city centre

Pool

Free Wi-Fi

Parking

$192

Avg. per night

View Deal

Other accommodation in Sikeston

Show all 16 stays

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane, Sikeston, MO, United States

4.8 km from city centre

Free Wi-Fi

Air conditioning

$102

Avg. per night

View Deal

Best Western Plus Sikeston

120 South Interstate Drive, Sikeston, MO, United States

5.3 km from city centre

Pool

Free Wi-Fi

Parking

$153

Avg. per night

View Deal

Holiday Inn Express & Suites Sikeston By IHG

115 Hospitality Drive, Sikeston, MO, United States

2.1 km from city centre

Pool

Free Wi-Fi

Parking

$192

Avg. per night

View Deal

Where to stay in Sikeston

Scroll to and zoom in on the areas in Sikeston you plan on visiting to find nearby properties. Users can click on a hotel's name to find more information about it, such as price, reviews, and amenities, and also find different deals for the property.

Facts about staying in Sikeston

What are the best hotels in Sikeston?
Drury Inn & Suites Sikeston is a very popular hotel in Sikeston, with a score of 9.3 from 1,244 reviews. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) (7.2 from 611 reviews) and Best Western Plus Sikeston (7.5 from 618 reviews) are also highly rated Sikeston hotels based on recent feedback from HotelsCombined users.
What are some other cities to stay in when visiting Missouri?
In addition to Sikeston, travellers opt to visit Kansas City when visiting Missouri.
How many hotels are there in Sikeston?
In total, there are 16 hotels to choose from in Sikeston, compared to 15,264 properties in Missouri.

Find better results for your stay in Sikeston

Hotels in Missouri

Travel insights for hotels in Sikeston

What is the cheapest month to book a hotel in Sikeston?

The cheapest month to book a hotel in Sikeston is January ($145). Conversely, the most expensive month to stay in Sikeston is September ($233).

What is the cheapest day to stay in a hotel in Sikeston?

The cheapest day to stay in Sikeston is Wednesday ($161). On the other hand, travellers can expect to pay the most on Friday, when the average nightly price is $234.

How far ahead should you book a hotel in Sikeston?

Save money by booking a hotel at least 46 days before your trip to Sikeston. The lowest price found when booking 46 days ahead was $105 per night.

Cheapest hotels in Sikeston, Missouri

Currently, these are the lowest-priced hotels in Sikeston we've come across for the dates selected. Prices can differ depending on the dates selected, so use the search form to browse more options if you have flexibility.

Other accommodation in Sikeston

Find the perfect hostel, theme hotel, or holiday rental for your stay in Sikeston.

Where to stay in Sikeston

Explore different neighbourhoods and areas within Sikeston to find the perfect location for your stay. Map data was last updated on 6 September 2026.

Scroll to and zoom in on the areas in Sikeston you plan on visiting to find nearby properties. Users can click on a hotel's name to find more information about it, such as price, reviews, and amenities, and also find different deals for the property.

Facts about staying in Sikeston

What are the best hotels in Sikeston?

What are some other cities to stay in when visiting Missouri?

How many hotels are there in Sikeston?

Find better results for your stay in Sikeston

Explore these cities in Missouri

Looking to explore Missouri during your trip? These are other popular cities nearby that HotelsCombined users visit

Visit Top Destinations

These destinations around the world are some of the most sought after locations from our users

Cities our users search for

Based on the last 12 months of user searches on HotelsCombined

Hotels in Sikeston

Search and compare Sikeston hotels from hundreds of travel sites on HotelsCombined and save.

Travel insights for hotels in Sikeston

What is the cheapest month to book a hotel in Sikeston?

The cheapest month to book a hotel in Sikeston is January ($145). Conversely, the most expensive month to stay in Sikeston is September ($233).

What is the cheapest day to stay in a hotel in Sikeston?

The cheapest day to stay in Sikeston is Wednesday ($161). On the other hand, travellers can expect to pay the most on Friday, when the average nightly price is $234.

How far ahead should you book a hotel in Sikeston?

Save money by booking a hotel at least 46 days before your trip to Sikeston. The lowest price found when booking 46 days ahead was $105 per night.

Cheapest hotels in Sikeston, Missouri

Currently, these are the lowest-priced hotels in Sikeston we've come across for the dates selected. Prices can differ depending on the dates selected, so use the search form to browse more options if you have flexibility.

Other accommodation in Sikeston

Find the perfect hostel, theme hotel, or holiday rental for your stay in Sikeston.

Where to stay in Sikeston

Explore different neighbourhoods and areas within Sikeston to find the perfect location for your stay. Map data was last updated on 6 September 2026.

Scroll to and zoom in on the areas in Sikeston you plan on visiting to find nearby properties. Users can click on a hotel's name to find more information about it, such as price, reviews, and amenities, and also find different deals for the property.

Facts about staying in Sikeston

What are the best hotels in Sikeston?

What are some other cities to stay in when visiting Missouri?

How many hotels are there in Sikeston?

Find better results for your stay in Sikeston

Explore these cities in Missouri

Looking to explore Missouri during your trip? These are other popular cities nearby that HotelsCombined users visit

Visit Top Destinations

These destinations around the world are some of the most sought after locations from our users

Cities our users search for

Based on the last 12 months of user searches on HotelsCombined