Hotels near Mayo Clinic, Rochester

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Popular hotels near Mayo Clinic

Discover well-known properties in Mayo Clinic that are favoured by visitors more than others. There are 85 hotels in Mayo Clinic and price data was last updated on 17 January 2026. The average price for a hotel in Mayo Clinic is .
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20 2nd Avenue Southwest, Rochester, MN, United States
Central Rochester hotel connected to the convention center, steps from Mayo Clinic 2 restaurants, an indoor pool, and a 24-hour fitness center are available at this smoke-free hotel. WiFi in public areas is free. Additionally, a bar/lounge, a sauna, and a 24-hour business center are onsite. Housekeeping is available once per stay. Kahler Grand Hotel offers 552 air-conditioned accommodations with coffee/tea makers and hair dryers. Beds feature premium bedding. Televisions come with cable channels and pay movies. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include bathtubs or showers and complimentary toiletries. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks and desk chairs, as well as phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is offered once per stay and change of bedsheets can be requested. Housekeeping is provided on a limited basis. An indoor pool and a hot tub are on site. Other recreational amenities include a sauna and a 24-hour fitness center. Children under 17 years old are not allowed in the swimming pool, fitness facility, or hot tub without adult supervision. The recreational activities listed below are available either on site or nearby; fees may apply.
Pool
Free Wi-Fi
6.9
Good
1831 reviews
Location
1.5 km from city centre
9 3rd Avenue Northwest, Rochester, MN, United States
Hotel with free breakfast, 3-minute walk to Mayo Clinic This smoke-free hotel features an indoor pool, a fitness center, and a coffee shop/cafe. Free self-serve breakfast and free WiFi in public areas are also provided. Other amenities include self parking, laundry facilities, and a 24-hour front desk. Housekeeping is available on request. Kahler Inn and Suites - Mayo Clinic Area offers 271 air-conditioned accommodations with coffee/tea makers and irons/ironing boards. Flat-screen televisions come with cable channels and pay movies. Rooms have partially open bathrooms. Bathrooms include showers and complimentary toiletries. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Housekeeping is provided on request. Recreational amenities at the hotel include an indoor pool and a fitness center. The recreational activities listed below are available either on site or nearby; fees may apply.
Pool
Free Wi-Fi
Airport shuttle
7.2
Good
2031 reviews
Location
1.6 km from city centre
10 East Center Street, Rochester, MN, United States
The Hilton Rochester Mayo Clinic Area is located in downtown Rochester two blocks from Mayo Clinic and one block from the Mayo Civic Center. Rochester International Airport is 8 miles away with flights to Chicago and Minneapolis. Minneapolis St. Paul International Airport is 80 miles away with frequent shuttle service. Interstate 90 is also 8 miles from downtown providing access from Madison, Chicago, and points east. The hotel offers spacious guest rooms and suites with Hilton bedding, work areas, seating, and free high speed internet. WiFi is available throughout and a Tech Lounge is located in the lobby. The fifth floor holds an indoor infinity pool, steam room, sauna, and outdoor rooftop terrace. Hilton Honors Gold members receive complimentary breakfast in the lounge and upgrades based on availability. Hilton Honors Diamond members receive complimentary lounge access and upgrades based on availability. Seven luxury suites are located on the top floor offering expansive accommodations with enhanced amenities. Guests in these suites have access to a dedicated concierge team providing personalized assistance with dining, transportation, and local arrangements for an elevated stay experience. The event center provides 24,000 sq. ft. of meeting and banquet space including two ballrooms with 19-foot ceilings, breakout rooms, and pre-function areas. Facilities feature modern audiovisual equipment and catering services for conferences, seminars, weddings, and receptions, with panoramic city views. The hotel connects to the city skyway system offering climate-controlled access to Mayo Clinic, Galleria at University Square mall, restaurants, the University of Minnesota Rochester campus, the Courthouse, and other downtown locations. Hilton Rochester Mayo Clinic Area combines a central location with contemporary design and personalized service for medical, business, and leisure travelers.
Pool
8.8
Excellent
186 reviews
Location
1.6 km from city centre
155 16th Avenue Southwest, Rochester, MN, United States
Hotel By St Mary's Hospital - Rochester Mayo Clinic Welcome to the Holiday Inn Express & Suites Rochester - Mayo Clinic Area hotel, located just 2.5 blocks west of St. Mary’s Hospital, and less than a mile from Mayo Clinic, the Gonda building, and the Eisenberg building. You'll find us on the corner of Hwy 52 and 2nd Street SW, making it easy to come and go as you please from our underground heated parking garage. Our hotel offers shuttle service to the hospital and clinic on weekdays for your convenience if you don't want to drive. And the Rochester International Airport is only 9 miles from us. The Rochester Holiday Inn Express is a great hotel for families while visiting the area. We are near some of Rochester's best attractions including the Mayo Civic Center, Silver Lake, Minnesota Children's Museum of Rochester, and the History Center of Olmsted County. After a long day, we hope you take the chance to visit one of the great local restaurants we have near the hotel like Canadian Honker, Cafe Presto, or Tonic that are just steps away from our door. We are even near popular chain restaurants including TGI Fridays, Olive Garden, and Famous Dave's. We hope your stay at the Holiday Inn Express Rochester, MN is a pleasant one.
Pool
Free Wi-Fi
Parking
8.1
Excellent
293 reviews
Location
1.8 km from city centre
165 13th Avenue Southwest, Rochester, MN, United States
Stay where health and service are just steps away. Located across the street is Saint Marys Hospital and less than a mile away is the Mayo Clinic Methodist campus. Feel at home in our spacious suites, equipped with modern amenities and thoughtful touches, ensuring a relaxing retreat after a day of exploration or medical appointments. Savor a complimentary hot breakfast each morning, unwind at our Wednesday evening social, and stay connected with free WiFi throughout the hotel. Our central location is within walking distance of a variety of restaurants and retailers. We’re just minutes from Downtown Rochester where you will find the Mayo Civic Center and Rochester Art Center. The Rochester International Airport is only a short drive away.
Pool
Free Wi-Fi
9.0
Excellent
139 reviews
Location
1.7 km from city centre
101 1st Avenue Southwest, Rochester, MN, United States
Directly connected to the Mayo Clinic, Rochester Marriott Mayo Clinic Area, hotel offers easy access to some of the city's most popular attractions via underground climate-controlled pedestrian walkways and skyways. Shop at University Square and enjoy biking, running and several trails nearby. Or visit Minneapolis and Saint Paul, an easy day trip from Rochester, MN. Host an event or board meeting in our hotel's modern venues or unwind after a busy day at our in new in house restaurant North Stone Kitchen. Business travelers, enjoy spacious guest rooms with work areas and Wi-Fi. All our guest rooms and suites feature luxurious bedding and HDTVs, plus a wealth of upscale amenities. Find modern luxury downtown Rochester at Rochester Marriott Mayo Clinic Area.
Pool
Free Wi-Fi
8.0
Excellent
296 reviews
Location
1.4 km from city centre
1211 2nd Street, Rochester, MN, United States
Hotel with free breakfast, steps from Mayo Clinic Hospital - Saint Marys Campus This smoke-free hotel features an indoor pool, a fitness center, and a 24-hour business center. Free full breakfast is provided, as well as free WiFi in public areas, free self parking, and a free area shuttle. Other amenities include a hot tub, coffee/tea in a common area, and a business center. Housekeeping is not available. Aspen Suites offers 82 air-conditioned accommodations with DVD players and safes. Accommodations offer separate sitting areas. Beds feature premium bedding. 32-inch flat-screen televisions come with premium cable channels. Accommodations at this 3-star hotel have kitchenettes with stovetops, microwaves, cookware/dishes/utensils, and dishwashers. Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include coffee/tea makers and irons/ironing boards. Housekeeping is offered daily and hair dryers can be requested. An indoor pool and a hot tub are on site. Other recreational amenities include a fitness center.
Pool
Free Wi-Fi
8.4
Excellent
175 reviews
Location
1.6 km from city centre
123 Fourth Ave. NW, Rochester, MN, United States
Hotel with free breakfast, 4-minute walk to Mayo Clinic A 24-hour business center, self parking, and laundry facilities are available at this smoke-free hotel. Free continental breakfast and free WiFi in public areas are also provided. Other amenities include a 24-hour front desk and free newspapers. Brentwood Inn & Suites offers 93 accommodations with complimentary newspapers and coffee/tea makers. Refrigerators and microwaves are provided. Guests can surf the web using the complimentary wireless Internet access. Flat-screen televisions come with premium cable channels. Irons/ironing boards and hair dryers can be requested. Housekeeping is provided daily.
Free Wi-Fi
7.9
Good
33 reviews
Location
1.7 km from city centre
441 West Center Street Northwest, Rochester, MN, United States
The Residence Inn Rochester Mayo Clinic Area is conveniently located downtown Rochester, MN within walking distance to the world-famous Mayo Clinic. Enjoy our newly renovated well-appointed 1 or 2 bedroom suite with a sofa bed, kitchen with microwave, full-size fridge, stovetop, dishwasher, and cookware. Complimentary amenities include a hot breakfast each morning, Wi-Fi access, a 24-hour fitness center, and a rooftop patio. Host up to 20 people for a business meeting in the Silver Lake Meeting room. The Residence Inn Rochester Mayo Clinic Area is 9 miles from the Rochester International Airport and provides access to Mayo Clinic via a indoor pedestrian walkway. Our hotel in downtown Rochester, MN is centrally located to St. Mary’s Hospital and Methodist Hospital. Please be aware there is on-going Mayo construction next to us, which may cause noise related concerns during your stay.
Free Wi-Fi
7.6
Good
93 reviews
Location
1.5 km from city centre

Cheapest hotels near Mayo Clinic, Rochester

Discover affordable stays in Mayo Clinic that provide a quality experience without breaking the bank. Hotels in Mayo Clinic can be found for as low as $114 per night. There is currently one property in Mayo Clinic that can be booked for this price. Baymont by Wyndham Rochester Mayo Clinic Area is one of the hotels that can be booked for the lowest price in Mayo Clinic. Price data was last updated on 17 January 2026
Out of the hotels close to Mayo Clinic we've come across, these properties are priced the lowest. Prices will typically fluctuate depending on the dates selected, star rating of hotel, and hotel location.
1230 South Broadway, Rochester, MN, United States
0.9 km from city centre
Pool
Free Wi-Fi
Parking
$114
Avg. per night
1215 2nd Street Southwest, Rochester, MN, United States
1.6 km from city centre
Free Wi-Fi
Parking
$144
Avg. per night
435 16th Avenue Northwest, Rochester, MN, United States
2.3 km from city centre
Pool
Free Wi-Fi
Parking
$149
Avg. per night
1125 2nd Street Southwest, Rochester, MN, United States
1.5 km from city centre
Pool
Free Wi-Fi
Parking
$188
Avg. per night
401 6th Street Southwest, Rochester, MN, United States
0.8 km from city centre
Pool
Free Wi-Fi
Parking
$196
Avg. per night
470 17th Avenue Northwest, Rochester, MN, United States
2.4 km from city centre
Pool
Free Wi-Fi
Parking
$196
Avg. per night
225 South Broadway, Rochester, MN, United States
1.4 km from city centre
Pool
Free Wi-Fi
$200
Avg. per night
161 13th Avenue Southwest, Rochester, MN, United States
1.7 km from city centre
Pool
Free Wi-Fi
$207
Avg. per night

Other accommodations in Mayo Clinic

Find the perfect hostel, theme hotel, or holiday rental for your stay in Mayo Clinic.
161 13th Avenue Southwest, Rochester, MN, United States
1.7 km from city centre
Pool
Free Wi-Fi
$207
Avg. per night
441 West Center Street Northwest, Rochester, MN, United States
1.5 km from city centre
Free Wi-Fi
$297
Avg. per night
225 South Broadway, Rochester, MN, United States
1.4 km from city centre
Pool
Free Wi-Fi
$200
Avg. per night

Where to stay in Mayo Clinic

Explore different neighbourhoods and areas within Mayo Clinic to find the perfect location for your stay. Map data was last updated on 17 January 2026.
Scroll through the map to find hotels close to the Mayo Clinic neighbourhood(s) you plan on visiting. You can find more information on a particular hotel within the map by clicking on its name.

Facts about staying in Mayo Clinic

Find useful tips and insights about staying in Mayo Clinic to help you make the most of your experience. FAQs were last updated on 17 January 2026.
  • What are the best hotels near Mayo Clinic?

    Kahler Inn And Suites (7.2/10 from 2,031 reviews), SpringHill Suites by Marriott Mayo Clinic Area/Saint Marys (8.4/10 from 404 reviews), and Hilton Garden Inn Rochester Downtown (8.4/10 from 399 reviews) are all highly-rated places to stay near Mayo Clinic.

  • What is a good hotel near Waikiki Beach?

    Waikiki Marina Resort At The Ilikai is a hotel near Waikiki Beach that is popular with HotelsCombined users, scoring 8.2 across 925 reviews.

  • What is a good hotel in Mayo Clinic near Denarau Island?

    For a good hotel near to Denarau Island, consider Hilton Fiji Beach Resort & Spa - it is rated 8.1/10 from 2,887 HotelsCombined reviews.

  • Is there a good hotel near Disneyland Park?

    If you’re visiting Disneyland Park then the nearby Best Western Plus Stovall's Inn is a popular hotel with HotelsCombined users (4,267 reviews scoring it at an average 8.5/10).

  • How much is a cheap hotel near Mayo Clinic?

    $90 per night is the cheapest Mayo Clinic hotel price found in our data from the last 72 hours.

  • What are the most popular landmarks to visit in Mayo Clinic?

    There’s so much to see and do in Mayo Clinic, but we’ve found that the most popular landmarks are Waikiki Beach, Denarau Island, and Disneyland Park. You’ll want to stay in Honolulu to visit Waikiki Beach, Nadi to visit Denarau Island, and Anaheim to visit Disneyland Park.

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